Notify-up colonoscopy charges low after particular stool-primarily based test

Follow-up colonoscopy rates low after positive stool-based test

Among a mean-threat population, practice-up colonoscopy (FU-CY) charges are low after a particular noninvasive stool-primarily based screening test (SBT) for colorectal cancer, in accordance to a gaze printed on-line Jan. 18 in JAMA Network Start.

Jeff T. Mohl, Ph.D., from the American Scientific Community Affiliation in Alexandria, Virginia, and colleagues conducted a blended-concepts gaze collectively with a retrospective prognosis of deidentified administrative claims and electronic health records records between June 1, 2015, and June 30, 2021, besides interviews with clinicians from five health care organizations to assess FU-CY charges after a particular SBT outcome. The cohort gaze included 32,769 contributors (mean age, 63.1 years).

The researchers chanced on that the FU-CY charges were 43.3, 51.4, and 56.1 p.c within 90, 180, and 360 days, respectively, of the actual SBT outcome. When interviewed, clinicians were uniformly bowled over by the low FU-CY charges. There modified into once variation observed in charges by speed, ethnicity, insurance coverage form, presence of comorbidities, and form of SBT outdated. The strongest particular association modified into once considered with multitarget stool DNA employ (hazard ratio, 1.63 relative to fecal immunochemical assessments), and the strongest detrimental association modified into once considered with the presence of comorbidities (hazard ratio, 0.64 for a Charlson Comorbidity Index >4 versus 0).

“At-house stool-primarily based testing gives a precious system to complement routine colonoscopy and attain a grand broader affected person population,” the authors write. “Nevertheless, it’s miles serious to stress that every particular SBTs will private to be followed by a properly timed colonoscopy to total the screening paradigm.”

The gaze modified into once funded by the Precise Sciences Corporation.

More records:
Jeff T. Mohl et al, Rates of Notify-up Colonoscopy After a Definite Stool-Basically primarily based Screening Take a look at Result for Colorectal Most cancers Among Successfully being Care Organizations within the US, 2017-2020, JAMA Network Start (2023). DOI: 10.1001/jamanetworkopen.2022.51384

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